Saturday, 29 March 2014

ADNESH

Antibiotic Dosage indication
IV CEFTRIAXONE 2g OD X 7/7 R LUNG EMPYEMA WITH UNDERLYING AFIB, AKI, DM
IV CLOXACILIN 1g OD X 7/7 Hospital acquired pneumonia
T AUGMENTIN 1.2g stat  AEBA secondary to CAP
T EES  800mg BD x 5/7 CAP
IV AUGMENTIN 1.2g TDS x 7/7 AECOPD secodnary to CAP
T EES 

IV Augmentin 
800mg BD x7/7
+
1.2g TDS x 7/7
CAP with underlying HPT DM Obesity
IV AUGMENTIN
+
IV AZITRHOMYCIN
1.2 TDSx 7/7
+
500mg OD x 3/7
CAP with AUR secondary to BPH
Oral Penicilin V
+
IV levofloxacin
250mg BD Ventilator related sepsis 
T Penicilin  250mh BD x 7/7 CAP with underlying DM


Most patients in the medical wards are prescribed with antibiotics are mainly related to respiratory tract infections, namely Pneumonia. Augmentin and Azitromycin are the commonly used broad spectrum antibiotic. Cloxacilin and penicillin group of antibiotic seemed to be more reserved for the severe cases and especially the nosocomial infections. Ceftriaxone and cephalosporin based antibiotic was given in the suspicion of gram negative bacterial infection such as the empyema. In my patients, the use of antibiotic is judicious and correct. 

Prepared by : Adnesh

Thursday, 27 March 2014

Michelle

Usage of antibiotics in the ward:




DETAILS
HISTORY/PHY EX/Ix
DIAGNOSIS
ANTIBIOTIC
DISCUSSION
1
56 y/o / M
k/c/o DM
·    Fever for 8 days with productive cough.
·Bibasal crepitations heard.
Community acquired pneumonia
·  IV Augmentin 1.2g TDS
·T. Azithromycin 500mg OD
Augmentin is usually used forB-lactamase producing strains of Strep pneu, H. infl, Moraxella C. Azithromycin (macrolide) used for CAP
2
40 y/o/ F
k/c/o BA
·    SOB for 2 days, with cough and wheezing
· Ronchi heard bilaterally
AEBA secondary to URTI
·  C. Amoxycillin 500mg TDS for 1 week
Amoxycillin is used for mild to moderate LRTI from Strep pneu, Staph, H. Influenzae.
3
51y/o / M
k/c/o COPD, HT, gout
·    SOB for 1 day, with cough
· Crepitations heard bibasally
AECOAD secondary to CAP
·  IV Augmentin 1.2g TDS
·T. Azithromycin 500mg OD

4
83 y/o /M
k/c/o HT
·    Confusion and disorientation of sudden onset
·    UFEME: UTI picture
Acute delirium secondary to UTI
·  IV Cefuroxime 750mg TDS
·IV Ciprofloxacin 200mg BD
Cefuroxime is 2nd gen cephalosporin (gram -ve). Used for UTI. Ciprofloxacin targets gram -ve and +ve 
5
55 y/o/ M
k/c/o DM
·    Jaundice for 6 days, high-grade fever for 2 months
·    Leptospira ag: +ve
·    Mycoplasma pneumonia: +ve
Leptospirosis infection with underlying lung infection
·  T. Doxycycline 100mg BD
·  IV Ceftriaxone 1g OD
Doxycycline is used for mycoplasma pneumoniae infection. Ceftriaxone is 3rd gen cephalosporin, mostly gram -ve B-lactamase bacilli
6
51 y/o/ F
k/c/o BA
·    SOB of sudden onset, with productive cough.
·    Bibasal crepitations
APO secondary to NSTEMI with CAP
·  T. EES 800mg BD
·  T. Augmentin 625mg BD

7
58y/o/ M
k/c/o COPD
·    SOB for 2 days, with productive cough. No fever.
·    Bibasal crepitations heard.
AECOAD secondary to CAP
·  IV Augmentin 1.2g TDS
·  T. EES 800mg BD
·  T. Ciprofloxacin 500mg BD
Patient's antibiotics were changed to Ciprofloxacin to prevent development of  antibiotic-resistant organisms.
8
50 y/o / M
k/c/o stage 4 lung cancer
·    Fever, cough, SOB for 2 days
·    Crepitations heard with reduced breath sounds over right lung zones.
Pleural effusion secondary to lung carcinoma with underlying CAP
·  IV Cefepime 2g OD
Cefepime is 4th gen cephalosporin. Susceptible organisms include E. coli, H. influenzae, Klebsiella, Staph aureus, Strep pyogenes. Used for CAP and UTI.
9
49 y/o/ F
k/c/o bronchiectasis
·    SOB for 2 days, fever for 5 days with productive cough
·    Coarse crepitations heard
Acute infective exacerbation of bronchiectasis secondary to CAP
·  IV Cefepime 2g BD

10
57 y/o/ F
k/c/o DM, HT, CKD, CCF, Thyrotoxicosis
·    SOB for 4 days with noisy breathing for 2 months. Fever=39 deg.
·    Intubated and ventilated in the ward.
·    UFEME: UTI picture
Sepsis secondary to CAP/UTI
·  IV Augmentin 1.2g TDS
·T. Azithromycin 500mg OD



In the wards, most of the patients diagnosed with community acquired pneumonia will usually be given a combination of broad-spectrum antibiotic of IV Augmentin and T. Azithromycin to cover both gram negative and gram positive organisms. In a case of UTI, usually cephalosporin-based antibiotics such as Cefuroxime or Ceftriaxone will be prescribed as most UTI organisms are gram negatives. 4th Generation cephalosporins such as Cefepime are prescribed in cases whereby both gram negative as well as gram positive organisms are suspected in an immunocompromised or immunosupressed patient. I feel that most of the antibiotics prescribed in the wards are appropriate with the presenting complaint and provisional diagnosis of the patient. However, there exists certain cases whereby antibiotics should not be prescribed. For instance, I feel that patient (2) should not be prescribed antibiotics as her AEBA is most likely exacerbated by the URTI that she had previously which is usually viral in origin. She did not even present with fever. Hence, I feel that this particular patient was wrongly prescribed antibiotics.